Relative Effect of High-Dose Influenza Vaccination on Hospitalizations of Older Adults in United States Nursing Homes: Results From a Cluster-Randomized Controlled Trial
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چکیده
LB-8. Relative Effect of High-Dose Influenza Vaccination on Hospitalizations of Older Adults in United States Nursing Homes: Results From a Cluster-Randomized Controlled Trial Stefan Gravenstein, MD, MPH; Monica Taljaard, PhD; Pedro Gozalo, PhD; Roshani Dahal, MPH; H. Edward Davidson, PharmD, MPH; Lisa Han, MPH; Jessica Ogarek, MS; Vincent Mor PhD; Medicine, Geriatrics, Case Western Reserve University, Cleveland, Ohio; Center for Gerontology and Healthcare Research, Brown University School of Public Health, Providence, Rhode Island; Center for Geriatric Medicine, University Hospitals Case Medical Center, Cleveland, Ohio; Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada; Department of Health Services, Policy and Practice, Brown University School of Public Health, Providence, Rhode Island; Insight Therapeutics, LLC, Norfolk, Virginia; Providence VA Medical Center, Providence, Rhode Island
منابع مشابه
Feasibility of a cluster-randomized influenza vaccination trial in U.S. nursing homes: Lessons learned
Influenza severity increases and vaccine effectiveness decreases with age. High-dose influenza vaccine (HD) with quadruple the antigen of standard-dose (SD) vaccine is more efficacious in community-dwelling persons 65 years and older. We evaluated the feasibility of recruiting and randomizing Medicare certified nursing homes (NHs) for a pragmatic cluster-randomized trial comparing HD vs. SD (NC...
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OBJECTIVES To evaluate the effect of staff influenza vaccination on all-cause mortality in nursing home residents. DESIGN Pair-matched cluster-randomized trial. SETTING Forty nursing homes matched for size, staff vaccination coverage during the previous season, and resident disability index. PARTICIPANTS All persons aged 60 and older residing in the nursing homes. INTERVENTION Influenza...
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References 1. Bittner MJ, Gorby GL, Parks CC. Absence of laboratoryconfirmed failures of high-dose influenza vaccine in an elderly population. WMJ. 2013;112(2):45. 2. Temte JL. Commentary: Solid evidence is lacking, but signs are hopeful. WMJ. 2013;112(2):45. 3. DiazGranados CA, Dunning AJ, Kimmel M, et al. Efficacy of high-dose versus standard-dose influenza vaccine in older adults. N Engl J M...
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